Pathology
PERIPHERAL NEUROPATHY ⇒ alcohol excess (vitamin B1/thiamine deficiency), B12 deficiency, diabetes, charcot-marie-tooth, vasculitis, HIV
PROXIMAL MYOPATHY ⇒ cushing’s, hyperthyroidism, myasthenia gravis (fatigable), dermatomyositis + polymyositis, LEMS
CEREBELLAR DISEASE ⇒ multiple sclerosis, alcohol, stroke, inherited ataxia, space occupying lesion
Unilateral LMN Lesions:
Unilateral UMN → stroke, SOL
Bilateral UMN → MS, MND (sensation normal), myelopathy (ie. cord compression)
Dorsal Column Pathways = light touch, vibration and proprioception
Spinothalamic = pain and temperature