• Define type 1 diabetes
• Diagram of diabetes classification
• What is the overlap between type 1 and 2 diabetes presentation?
• Why is the fact that T1DM can develop in adults important?
• Graph of stages of development of type 1 diabetes
• Another diagram of immune system at different stages of T1DM
• Describe this image of immune infiltration of islets
• Why is the immune basis of T1DM important?
• What is the mechanism of the autoimmune destruction of beta cells in T1DM?
• Are all beta cells destroyed in T1DM?
• What gene mediates genetic susceptibility to T1DM?
• What does this genome-wide association study show?
• What environmental factors are there that affect T1DM?
• What are the symptoms of T1DM? (7)
• What are the signs of T1DM? (6)
• What is diagnosis of T1DM based on?
• What pancreatic auto-antibodies could we measure in T1DM patients? (4)
• What does a lack of insulin cause in the body? (3)
• What are the aims of treatment in type 1 diabetes? (4)
• What are the types of complications of T1DM?